Vascular Ehlers-Danlos syndrome (vEDS)

Vascular Ehlers-Danlos syndrome (vEDS) is a familial (or inherited) condition. People with the condition may have a wide range of features that range from spontaneous and easy bruising with little or no change in lifespan to bowel and/or arterial ruptures. Women with vEDS have the potential of a rupture of the uterus during pregnancy that may substantially shorten lifespan. Some people with vEDS have  a characteristic facial appearance, thin skin, and tissue fragility that could indicate the condition is present before there is a  major complication.

Vascular EDS is caused by mutations in COL3A1, a gene that directs the synthesis of type III collagen that is a major component of blood vessels, bowel walls, and skin. The diagnosis is generally suspected through a clinical exam because other family members are affected or because of a bowel or arterial rupture and then is confirmed by genetic testing.

  • What other names do people use for vascular Ehlers-Danlos syndrome?
  • How prevalent is vascular Ehlers-Danlos syndrome?
  • What are the characteristics of vascular Ehlers-Danlos syndrome?
  • What is the cause of vascular Ehlers-Danlos syndrome?

Find these answers and more in the vascular Ehlers-Danlos syndrome download.

Vascular Ehlers-Danlos Syndrome