Current Research

We always work tirelessly to advance research that saves lives and dramatically enhances the quality of life for people living with Marfan syndrome and related conditions. The research that we’ve supported has helped reduce life-threatening problems from these conditions, identified treatments that have improved the quality of life, and helped people to live a long life with Marfan syndrome and related conditions. We continue to support this research because we know there are still people struggling on their medical journey.

As a result of our long-time commitment to advancing this research, we have turned the tide for Marfan research. We work with world-class scientists who are equally dedicated to our goal of creating a brighter future for people living with Marfan syndrome and related disorder. And, through our research grant program, we have grown the number of researchers studying Marfan syndrome and advancing research that improves diagnosis and treatment for all different body systems affected by Marfan syndrome.

In addition, the research we’ve championed has identified new disorders related to Marfan syndrome, which not only allows for better, more specific diagnoses, but also helps to pinpoint more effective treatments for Marfan syndrome and the related conditions.

To expand the impact of our efforts, we push the government to fund the research that will improve and save lives. Further, we facilitate the sharing of knowledge about Marfan syndrome and related conditions through conferences, symposia, and partnerships with governmental agencies and other health organizations. We continue to move forward research for both Marfan syndrome and related conditions because advances in fighting Marfan syndrome helps us take steps toward victory in related conditions—and vice versa.

Each year, The Marfan Foundation pursues the most innovative reserach by providing support through our research grant program.  In 2017, we received 27 proposals and awarded nine research grants to scientists ranging from seasoned investigators to young researchers.  Seven of those grants were awarded to first time applicants, helping to expand our circle of researchers.  Through our grant program and other commitments, we funded $1.5 million dollars in research this year.  As a result of our efforts, grants will help researchers:

  • Study eye issues in Marfan syndrome and other connective tissue conditions.
  • Investigate factors that might be protective against aortic dissection in Marfan syndrome.
  • Explore new unique therapeutic targets to combat the devastating aortic issues in Marfan syndrome.
  • Seek a better understanding of the bones in Marfan syndrome so that additional treatment options can be identified.
  • Gain knowledge about how surgical grafts affect native aortic tissues.
  • Test the impact of losartan on blood vessel health.
  • Investigate new therapies to slow or prevent aortic enlargement in Marfan syndrome.
  • Explore the durability of aortic valve-sparing surgery. After providing more than $1.1 million to a critically important study on the short-term durability of aortic valve-sparing surgery, we are now also exploring the long-term durability of this valve-sparing procedure by providing funding for an additional 10-year period.

To read more about the research grants we most recently awarded, click here.

You can help us advance research on Marfan syndrome and related disorders by providing financial support and by participating in research studies. We hope you will join us in our fight for victory.