Funded Research Grants | The Marfan Foundation

Funded Research Grants

2016

  • Maryline Abrial, PhD, Massachusetts General Hospital, Investigating a Novel Genetic Model of Aortic Root Aneurysm in Zebrafish, $100,000 2-year McKusick Fellowship Grant
  • Vallabhajosyula Prashanth MD, MS, University of Pennsylvania, Plasma Endothelial Specific Exosome Profiling in Marfan Syndrome, $75,000 2-year Early Investigator Grant
  • Rouf Rosanne MD, Johns Hopkins School of Medicine, Using an Established MFS Mouse Model to Understand MVP Pathogenesis, $75,000 2- year Early Investigator Grant
  • Dr. Suneel Apte, MBBS, DPhil, Cleveland Clinic, Fibrillin Microfibril Regulation by ADAMTSL3, $100,000 2-year Faculty Grant
  • Seda Tierney, MD, Stanford University and Mitra Esfandiarei, Ph.D. Midwestern University, Children and Adolescents with Marfan Syndrome: 10,000 Healthy Steps and Beyond, $100,000 2-year Faculty Grant
  • Zhiyong Lin, PhD, Case Western Reserve University, Allosteric Activation of PP2A to Limit the Progression of Aortic Aneurysm in Marfan Syndrome, $100,000 2-year Faculty Grant 
  • Jessica Wagenseil, DSc, Washington University, Arterial Tortuosity and Aneurysms, $100,000 2-year Faculty Grant

2015

  • Emanuela Branchetti, PhD, University of Pennsylvania, RAGE/sRAGE Axis: Novel Biomarker and Mechanism of Ascending Aortic Aneurysm Development in Marfan Syndrome. $75,000 2-year Early Investigator Grant
  • Mitra Esfandiarei, PhD, Midwestern University, Role of Caveolin-1 in the Progression of Aortic Aneurysm in Marfan Syndrome. $75,000 2-year Early Investigator Grant
  • Parmanand Singh, MD, Weill Cornell Medical College, Predictive Value of Inflammation and Arterial Stiffness in Thoracic Aortic Aneurysm. $75,000 2-year Early Investigator Grant
  • Lakshmi Venkatraman PhD, Beth Israel Deaconess Medical Center, Systems Biology of Tgfb in Vascular Complications of Marfan Syndrome. $100,000 2-year McKusick Fellowship Grant
  • Gustavo Egea, PhD, Institut d’Investigacions Biomediques August Pi I Sunyer (IDIBAPS), Apolinker P144: A Potential anti-TGF-b Therapeutic Tool to Fight Against Aortic Aneurysms in Marfan Syndrome. $80,000 2-year Faculty Grant
  • Christina Gurnett, MD, PhD, Washington University School of Medicine, Zebrafish Models of Human Fibrillinopathies. $100,000 2-year Faculty Grant
  • Francesco Ramirez, PhD, Icahn School of Medicine at Mount Sinai, Endothelial Dysfunction as the Trigger of Aortic Aneurysm in the Marfan Syndrome. $100,000 2-year Faculty Grant
  • Daniel Rifkin, PhD, New York University School of Medicine, Genetic Interrogation of the Role of LTBPs in Aortic Aneurysms. $100,000 2-year Faculty Grant

2014

  • Dirk Hubmacher, PhD, Cleveland Clinic Foundation, Promotion of Microfibril Assembly in Aortic Smooth Muscle Cells in a Mouse Model for Marfan Syndrome. $75,000 2-year Early Investigator Grant
  • Douglas Mah, MD, Boston Children’s Hospital, Ventricular Ectopy and other Rhythm Abnormalities in Children and Young Adults. $37,375  1-year Early Investigator Grant
  • Francesca Seta, PhD, Boston University School of Medicine, Sirtuin1 in Aortic Remodeling and Dissection. $75,000 2-year Early Investigator Grant
  • David Alvarado, PhD, Washington University, Expanding the Spectrum of Fibrillin Mutations in Marfan Syndrome and Related Disorders. $100,000 2-year McKusick Fellowship Grant
  • Elona Gavazi, MD, Columbia University Medical Center, Characterizing the Ophthalmalmic Phenotype of Marfan Syndrome Mouse Model and Demonstrating Pre-Clinical Efficacy of Preventative Therapeutic Interventions in this Heterozygous Model. $150,000 2-year McKusick Fellowship Grant
  • Steven Bassnett, PhD, Washington University School of Medicine, Role of Microfibrils in the Biology and Pathology of the Eye. $100,000 2-year Faculty Grant
  • Silvia Smaldone, PhD, Icahn School of Medicine at Mount Sinai, Characterization of Long Bone Overgrowth in Marfan Syndrome. $100,000 2-year Faculty Grant
  • Dudley Strickland, PhD, Role of LRP1 in Regulating Development of Marfan Syndrome. $100,000 2-year Faculty Grant

2013

  • Michael Fischbein, MD, Stanford University, Role of MicroRNA-29b during Aneurysm Formation in Aortic Segments of Different Embryologic Origin. $75,000 2-year Early Investigator Grant
  • Hadas Shiran, MD, Stanford University School of Medicine, Risk Factors for Complications of Thoracic Aortic Aneurysms. $75,000 2-year Early Investigator Grant
  • Venkateswaran Subramanian, PhD, University of Kentucky Research Foundation, Role of Calpain in AngII-induced Ascending Aortic Aneurysm. $75,000 2-year Early Investigator Grant
  • Josephine Galatioto, PhD, Mount Sinai School of Medicine, Characterization of Putative Triggers of Early Thoracic Aortic Aneurysm in Marfan Syndrome. $100,000 2-year McKusick Fellowship Grant
  • Sarah J. Parker, PhD, Cedars-Sinai Medical Center, Determination of the Molecular Mechanisms that Underlie the Anatomical Specificity of Aortic Aneurysm in Marfan Syndrome. $100,000 2-year McKusick Fellowship Grant
  • Rachel Kuchtey, MD, PhD, Vanderbilt University, Glaucoma in a Mouse Model of Marfan Syndrome. $100,000 2-year Faculty Grant
  • Lynn Y. Sakai, PhD, Shriners Hospital for Children, Targeting Collaborative Signaling Pathways in Marfan Syndrome. $100,000 2-year Faculty Grant
  • Chen Yan, PhD, University of Rochester, Vascular Smooth Muscle Cell Phenotype Transition and Thoracic Aortic Aneurysm in Marfan Syndrome. $100,000 2-year Faculty Grant